This paper presents a prototype FPGA design for an efficient physical layer of MIMO-OFDM technique for advanced Long Term Evolution of UMTS mobile communication. Advanced LTE has become the preferred system for broadband access, Multimedia Messaging Services (MMS), Video Chat, mobile TV and Digital Video broadcasting. However, Orthogonal Frequency Division Multiplexing (OFDM) and Multiple Input Multiple Output (MIMO) are considered the key technology for increasing both data rates and system performance. On the other hand, the phase noise and the offset in frequency will destroy the orthogonality of the sub-carriers in practical Voltage Controlled Oscillator (VCO) in OFDM-MIMO system. The paper describes a 5.2 GHz-VCO as a key component in LTE transceivers. A model for phase noise and figure-of-merit is introduced and verified through simulation in a standard 0.13 lm CMOS process. A new nanometer negative resistance MOSFET (NRMOSFET) is used as a controllable negative resistance to compensate for the nanometer metamaterial losses. This model can be used as a core cell for LTE mobile communication smart antenna of a MIMO-OFDM technique. The model is implemented in programmable logic devices such as FPGAs and PLDs.