Migration of virtual machines transfers the state of a virtual machine from one physical machine to another, and can help mitigate overload conditions, assist in load balancing and server consolidation. Although a beneficial technique, the great amount of data to be transferred during migration causes performance degradation of the virtual machine because of increased migration time along with the increased network overhead. To solve the problem, this paper presents the design and implementation of a novel memory serialization and compression based migration approach that uses serialization to reduce the page dirty rate during memory transfer, and compression to reduce the total amount of data to be transferred.