With the expeditious evolution in the field of computer networks, the cases of network intrusions and exploitations have increased to a great extent. ARP spoofing attack, an appalling technique that makes use of ARP protocol’s defaults to assault the network and thereby destroying the communication between hosts by sending wrong IP/MAC addresses is one of the most being researched areas for preventive measures today. Even though large numbers of security measures have cropped up across the globe for prevention of ARP spoofing attacks but each approach lacks from different aspects. This paper proposes an idea to detect ARP poisoning in large organizations by verifying the authenticity of the user keeping in view the information maintained in the tables and using detection systems working independently at different departmental levels, in an effective way. In comparison to existing approaches worldwide, the proposed approach is more promising in terms of speed, perception and adaptability in different network scenarios. Thus, this paper is an endeavor to provide a holistic approach to solve the problem of man-in-the-middle attacks in wireless networks.