Periodic behavior has been a successful feature in cellular processes and biological processes that are highly contaminated with noise problem. In this paper, we introduce the use of a new test procedure for finding periodic sequence in multiple series or microarray data, with respect to hypothesis testing method based on the Fisher g‑statistic. Using the basic idea underlying a robust testing procedure under the Gaussian noise assumption, a computational efficiency means of detecting periodicity in biological time series data was established.

periodic behavior, cellular processes, periodic sequence, Fisher g-statistic.