In Alexander et al. [4] paper “ABO blood type factor VIII and incident cognitive impairment in the regards cohort”, which was published in American Academy of Neurology in 2014; their study which consists of 30329 45+ individuals registered between 2003 and 2007 shows that it is more frequent in ABO controls than the other blood types (A, B, O). Specifically, FVIII is significantly different with ABO blood group. According to this, the geographical and racial differences in coronary heart disease, cardiovascular diseases, FVIII, by dementia and strokes and their causes are made into account.

In the study, which was made extensively in the national diagnosis and treatment guide, it was described for FVIII for the first time by Geri at 1954. It was found that the congenital absence of FV and FVIII together is a very rare factor absence which proceeds with blooding. It is very rare in general total (1:1000000) but it is seen in men and women with equal proportions. It is seen in Mizrahi Jews, in which the relative marriages are commonly seen and in the non-Jew Iranians (1:100000). The absence of FV together with FVIII forms 3 percent of rare blooding disorders.

We are working with a younger community, because some of these differences have not been effective in this generation yet. One of the results reported in the paper is that the ABO group affects the cardiovascular risk and it has an active role in cognitive disorder and by dementia. We will try to explain the outcome of this result with a statistical research which involves finding the blood type that might be the source of the cognitive disorders (if any) of students who have enrolled into different science departments of universities.

blooding disorder, blood groups, FV, FVIII.