Advances and Applications in Statistics
Volume 21, Issue 2, Pages 105 - 124
(April 2011)
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DECISION SUPPORT SYSTEM FOR THE CLASSIFICATION OF BREAST CANCER DIAGNOSIS USING ROC
Medhat Mohamed Ahmed Abdelaal, Hala Abou Sena, Muhamed Wael Farouq and Abdel Badeeh Mohamed Salem
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Abstract: The objective of this study is to develop intelligent decision support system to aid radiologist in diagnosis using pattern recognition techniques to estimate diagnostic function. In this study, 3 approaches investigated namely, statistical, neural networks and optimization techniques which were applied on the Wisconsin dataset. Trained neural networks, with the data set used as input, improve on the independent variables LDF and LR for discriminating between true and false cases. The performance of Multilayer Perceptrons, Delta-Bar-Delta neural networks, LDF and LR can be improved with optimization of the features in the input. Neural network analyses show promise for increasing diagnostic accuracy of classifying the cases. The areas under the ROC curves for MLP and DBD were 0.929 and 0.927, respectively. For the full models of LDF and LR were 0.887 and 0.917, respectively. With the use of forward selection (FS) and backward elimination (BE) optimization techniques, the areas under the ROC curves for MLP and LR were increased to approximately 0.93. |
Keywords and phrases: breast cancer, multilayer perceptrons (MLP), back-propagation (BP), Delta-Bar-Delta (DBD), linear discriminant function (LDF), logistic regression (LR), receiver operating characteristic curve (ROC). |
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